Editorial: Bioactive Compounds from Microbes

Editorial: Bioactive Compounds from Microbes

Editorial on the Research Topic Bioactive Compounds from Microbes Microorganisms are ubiquitous and essentially interact with all the other organisms present in the biosphere, sometimes creating a network of signals that constitutes the basis for life on the Earth. Clarifying the nature of these molecular signals, their targets and the pathways underlying their production, constitutes the essen...

Exploring novel bioactive compounds from marine microbes.

The historical paradigm of the deep ocean as a biological 'desert' has shifted to one of a 'rainforest' owing to the isolation of many novel microbes and their associated bioactive compounds. Recently, there has been an explosion of information about novel bioactive compounds that have been isolated from marine microbes in an effort to further explore the relatively untapped marine microbes and...

Screening of Bioactive peptides from marine microbes

Bioactive compounds from Rumex plants

Two new naphthalene acylglucosides, rumexneposides A (1) and B (2), together with 12 known compounds (3-14), were isolated from the roots of Rumex nepalensis. Their structures were established by chemical and spectroscopic methods. The biological activities of compounds 1-14 as well as an additional 11 compounds previously isolated from R. nepalensis and Rumex hastatus (15–25) were evaluated ag...

Bioactive compounds from coral reef invertebrates*

Manzamine A (1) known as a cytotoxin exhibited potent antimalarial activity with 40% recovery 60 days after single intraperitoneal (i.p.) injection against mice infected with the malaria parasite Plasmodium berghei. Pachastrisamine (6), a simple derivative of a sphingosine, isolated from a sponge, Pachastrissa sp. showed a high level of cytotoxicity. New sesquiterpene carbonimidic dichlorides a...